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ZNF496 antibody

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产品名称: ZNF496 antibody
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产品展商: immunoclone
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简单介绍

抗ZNF496 antibody的**原：针对人ZNF496的中间区域的合成肽，ZNF496 antibody包含SCAN盒，KRAB-A结构域和四个共有C2H2型锌指，其前面是独特的手指衍生物，本文称为C2HR基序。 C2HR基序用于介导与Zn（II）依赖的NSD1的富含半胱氨酸（C5HCH）结构域的蛋白质 - 蛋白质相互作用。


ZNF496 antibody  的详细介绍

ZNF496 antibody     Product Profile

Product Name Rabbit anti-ZNF496 polyclonal antibody - middle region
Antibody Type Primary Antibodies
Immunogen 
The immunogen for anti-ZNF496 antibody: synthetic peptide directed towards the middle region of human ZNF496

ZNF496 antibody     Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WB

Species Reactivity

BovineDogHorsePigSheep

Concentration 1mg/ml
Purification Affinity purified

ZNF496 antibody    Target Information

Gene Symbol ZNF496
Gene Synonyms
ZNF496
Gene Full Name Zinc finger protein 496
Gene Summary
ZNF496 contains a SCAN box, a KRAB-A domain, and four consensus C2H2-type zinc fingers preceded by a unique finger derivative, referred to herein as the C2HR motif. The C2HR motif functions to mediate protein-protein interaction with the cysteine-rich (C5HCH) domain of NSD1 in a Zn(II)-dependent fashion, and when tethered to RNA polymerase II promoters, represses transcription in an NSD1-dependent manner. ZNF496 contains a novel type of zinc finger motif that functions as a docking site for NSD1 and is more than just a degenerate evolutionary remnant of a C2H2 motif.
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Alternative Names
MGC15548
NIZP1
ZKSCAN17
ZFP496
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Molecular Weight(MW) 67kDa
Sequence 587 amino acids

ZNF496 antibody    Database Links

Entrez Gene 84838
SwissProt ID Q96IT1
Protein Accession NP_116141

ZNF496 antibody   Application

  • ZNF496 antibody
    Application

    WB Suggested Anti-ZNF496 Antibody Titration: 0.2-1 ug/ml
    ELISA Titer: 1:12500
    Positive Control: PANC1 cell lysate

Additional Information

Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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