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CRK antibody

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产品名称: CRK antibody
产品型号:
产品展商: immunoclone
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简单介绍

CRK antibody迅速增长的产品线包括一抗、二抗、**测定及细胞检测试剂盒、蛋白/多肽、激动剂/拮抗剂/活化剂/抑制剂及裂解物等。CRK antibody严格的质量控制和验证实验包括各种不同的应用：WB、细胞**荧光、**组化、流式细胞术、ELISA、CHIP、IP和peptide array。


CRK antibody  的详细介绍

CRK antibodyProduct Profile

Product Name Rabbit anti-CRK polyclonal antibody - C-terminal region
Antibody Type Primary Antibodies

CRK antibodyKey Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WB

Species Reactivity

BovineDogGuinea PigHorseHumanMouseRat

Concentration 1mg/ml
Purification Affinity purified

CRK antibodyTarget Information

Gene Symbol CRK
Gene Synonyms
CRKII
p38
Gene Full Name V-crk sarcoma virus CT10 oncogene homolog (avian)
Gene Summary
This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.
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Alternative Names
CRKII
p38
Molecular Weight(MW) 34kDa
Sequence 304 amino acids

CRK antibodyDatabase Links

Entrez Gene 1398
SwissProt ID P46108
Protein Accession NP_058431

CRK antibodyApplication

  • Western blot

    Titration: 1.0 ug/ml
    Positive Control: Transfected 293T

Additional Information

Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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