Product Name	Rabbit anti-STAT6 polyclonal antibody - C-terminal region
Antibody Type	Primary Antibodies
Immunogen	The immunogen for anti-STAT6 antibody: synthetic peptide directed towards the C terminal of human STAT6

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Applications	WBIHC
Species Reactivity	BovineDogHorseHumanMousePigRabbitRat
Concentration	1mg/ml
Purification	Affinity purified

Gene Symbol	STAT6
Gene Synonyms	D12S1644 IL-4-STAT STAT6B STAT6C More
Gene Full Name	Signal transducer and activator of transcription 6, interleukin-4 induced
Gene Summary	Full-length human STAR6 (NP_003144) was expressed in E.coli as inclusion body and purified after protein refolding for mouse immunization. Clone 5B1 shows excellent western blot detection of endogenous STAT6 using ACHN cell lysate.The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. More
Alternative Names	D12S1644 IL-4-STAT STAT6B STAT6C More
Molecular Weight(MW)	94kDa
Sequence	847 amino acids

Form	Liquid
Storage Instructions	Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer	phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

STAT6 antibody