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COPS5 antibody

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产品名称: COPS5 antibody
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产品展商: immunoclone
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简单介绍

COPS5 antibody迅速增长的产品线包括一抗、二抗、**测定及细胞检测试剂盒、蛋白/多肽、激动剂/拮抗剂/活化剂/抑制剂及裂解物等。COPS5 antibody严格的质量控制和验证实验包括各种不同的应用：WB、细胞**荧光、**组化、流式细胞术、ELISA、CHIP、IP和peptide array。


COPS5 antibody  的详细介绍

COPS5 antibodyProduct Profile

Product Name Rabbit anti-COPS5 polyclonal antibody - N-terminal region
Antibody Type Primary Antibodies
Immunogen 
The immunogen for anti-COPS5 antibody: synthetic peptide directed towards the N terminal of human COPS5

COPS5 antibodyKey Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WB

Species Reactivity

BovineDogHorseHumanMousePigRat

Concentration 1mg/ml
Purification Affinity purified

COPS5 antibodyTarget Information

Gene Symbol COPS5
Gene Synonyms
CSN5
JAB1
MGC3149
MOV-34
SGN5
More 
Gene Full Name COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
Gene Summary
COPS5 is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
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Alternative Names
CSN5
JAB1
MGC3149
MOV-34
SGN5
More 
Molecular Weight(MW) 37kDa
Sequence 334 amino acids

COPS5 antibodyDatabase Links

Entrez Gene 10987
SwissProt ID Q92905
Protein Accession NP_006828

COPS5 antibodyApplication

  • Western blot

    Sample Type: 1. Human blood cells, pure
    2. Human blood cells, partially purified
    3. and 4. Human total cell extract, extraction only
    Primary Dilution: 1:500
    Secondary Anitbody: HRP conjugated anti-rabbit
    Image Submitted By: Dr. Elah Pick
    University of Haifa at Oranim 

Additional Information

Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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