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PPARGC1A antibody

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产品名称: PPARGC1A antibody
产品型号:
产品展商: immunoclone
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简单介绍

PPARGC1A antibody迅速增长的产品线包括一抗、二抗、**测定及细胞检测试剂盒、蛋白/多肽、激动剂/拮抗剂/活化剂/抑制剂及裂解物等。PPARGC1A antibody严格的质量控制和验证实验包括各种不同的应用：WB、细胞**荧光、**组化、流式细胞术、ELISA、CHIP、IP和peptide array。


PPARGC1A antibody  的详细介绍

PPARGC1A antibodyProduct Profile

Product Name Rabbit anti-PPARGC1A polyclonal antibody - N-terminal region
Antibody Type Primary Antibodies
Immunogen 
The immunogen for anti-PPARGC1A antibody: synthetic peptide directed towards the N terminal of human PPARGC1A

PPARGC1A antibodyKey Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

IFWB

Species Reactivity

BovineDogGoatHorseHumanMousePigRabbitRat

Concentration 1mg/ml
Purification Affinity purified

PPARGC1A antibodyTarget Information

Gene Symbol PPARGC1A
Gene Synonyms
LEM6
PGC-1(alpha)
PGC-1v
PGC1
PGC1A
PPARGC1
More 
Gene Full Name Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
Gene Summary
PPARGC1A is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
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Alternative Names
LEM6
PGC-1(alpha)
PGC-1v
PGC1
PGC1A
PPARGC1
More 
Molecular Weight(MW) 91kDa
Sequence 798 amino acids

PPARGC1A antibodyDatabase Links

Entrez Gene 10891
SwissProt ID Q9UBK2
Protein Accession NP_037393

PPARGC1A antibodyApplication

  • Immunofluorescence

    Mouse retina 
    Primary Antibody Dilution :
    1:200 
    Secondary Antibody :
    Donkey anti rabbit-Cy3
    Secondary Antibody Dilution :
    1:1000 
    Color/Signal Descriptions :
    Red: PPARGC1A
    Gene Name :
    PPARGC1A
    Submitted by :
    Dr. Joshua Sanes

  • Western blot

    0.2-1 ug/ml
    ELISA Titer: 1:62500
    Positive Control: Jurkat cell lysate

Additional Information

Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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