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N-Myc Antibody

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产品名称: N-Myc Antibody
产品型号:
产品展商: immunoclone
产品文档: 无相关文档

简单介绍

N-Myc Antibody迅速增长的产品线包括一抗、二抗、**测定及细胞检测试剂盒、蛋白/多肽、激动剂/拮抗剂/活化剂/抑制剂及裂解物等。N-Myc Antibody严格的质量控制和验证实验包括各种不同的应用：WB、细胞**荧光、**组化、流式细胞术、ELISA、CHIP、IP和peptide array。


N-Myc Antibody  的详细介绍

N-Myc AntibodyProduct Profile

Product Name N-Myc Antibody (C-19)
Antibody Type Tags Antibodies
Modification Notes The v-Myc oncogene, initially identified in the MC29 avian retrovirus, causes myelocytomas, carcinomas, sarcomas and lymphomas (1), and belongs to a family of oncogenes conserved throughout evolution. In humans, the family consists of five genes: c-Myc, N-Myc, R-Myc, L-Myc and B-Myc (2). Amplification of the N-Myc gene has been found in human neuroblastomas and cell lines (3,5). The extent of N-Myc amplification correlates well with the stage of neuroblastoma disease (4). Immunological studies have shown that the human N-Myc gene encodes a nuclear phosphoprotein (2) that exhibits relatively short (30 min) half life in vivo. The prototype member of the family, c-Myc p67, binds DNA in a sequence-specific manner subsequent to dimerization with a second basic region helix-loop-helix leucine zipper motif protein, designated Max (5-7).

N-Myc AntibodyKey Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WBIPIFELISA

recommended for detection of N-Myc of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian:
Species Reactivity

HumanMouseRat

Concentration 200 µg/ml
Purification Affinity purified

N-Myc AntibodyTarget Information

Alternative Names
epitope mapping within the C-terminus of N-Myc of human origin
Tissue Specificity epitope mapping within the C-terminus of N-Myc of human origin

N-Myc AntibodyDatabase Links

Entrez Gene 4613

N-Myc AntibodyApplication

  • Application

    Western blot analysis of N-Myc expression in non-transfected: (A) and mouse N-Myc transfected: (B) 293T whole cell lysates.

Application Notes
recommended for detection of N-Myc of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian:

Additional Information

Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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