Receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with SRC and CTNNB1/beta-catenin.1) Buerger C, et al. (2003) J Biol Chem; 278 (39): 37610-21. Wang XQ, (2003) J Biol Chem; 278 (49): 48770-8. Saito T, et al. (2004) Endocrinology; 145 (9): 4232-43. Pao W, et al. (2004) Proc Natl Acad Sci U S A; 101 (36): 13306-11. More
EGFR (Phospho-Tyr1092) antibody was raised against a peptide sequence around phosphorylation site of tyrosine1092 (P-E-Y (p) -I-N) derived from Human EGFR.
IHC
MouseRat
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using EGFR (Phospho-Tyr1092).
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