Receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with SRC and CTNNB1/beta-catenin.1) Doherty JK, et al. (1999) Proc Natl Acad Sci U S A; 96 (19): 10869-10874Wu TT, et al. (1998) Mol Biol Cell; 9 (7): 1661-1674O’Rourke DM, et al. (1997) Proc Natl Acad Sci U S A; 94 (7): 3250-3255Noguchi T, et al. (1994) Mol Cell Biol; 14 (10): 6674-6682Kanner SB, et al. (1991) Mol Cell Biol; 11 (2): 713-720 More
EGFR (Phospho-Thr693) antibody was raised against a peptide sequence around phosphorylation site of threonine 693 (P-L-T (p) -P-S) derived from Human EGFR.
WB
HumanMouseRat
Western blot analysis of lysed extracts from HUVEC cells untreated or treated with EGF using EGFR (Phospho-Thr693).
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