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EGFR (phospho Ser1070) Antibody

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产品名称: EGFR (phospho Ser1070) Antibody
产品型号:
产品展商: immunoclone
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简单介绍

EGFR (phospho Ser1070) Antibody迅速增长的产品线包括一抗、二抗、**测定及细胞检测试剂盒、蛋白/多肽、激动剂/拮抗剂/活化剂/抑制剂及裂解物等。EGFR (phospho Ser1070) Antibody严格的质量控制和验证实验包括各种不同的应用：WB、细胞**荧光、**组化、流式细胞术、ELISA、CHIP、IP和peptide array。


EGFR (phospho Ser1070) Antibody  的详细介绍

EGFR (phospho Ser1070) AntibodyProduct Profile

Product Name EGFR (phospho Ser1070) Antibody
Antibody Type Primary Antibodies
Product description 
					

						Receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with SRC and CTNNB1/beta-catenin.1) Feinmesser RL, et al. (1999) J Biol Chem; 274 (23): 16168-73. Gamou S, et al. (1995) FEBS Lett; 357 (2): 161-4. Gamou S, et al. (1994) J Cell Physiol; 158 (1): 151-9. Heisermann GJ, et al. (1988) J Biol Chem; 263 (26): 13152-8.
					

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Immunogen 
EGFR (Phospho-Ser1070) antibody was raised against a peptide sequence around phosphorylation site of serine 1070 (R-Y-S (p) -S-D) derived from Human EGFR.

EGFR (phospho Ser1070) AntibodyKey Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

IHCWB

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
Species Reactivity

HumanMouseRat

Concentration 1mg/ml
Purification Affinity purified

EGFR (phospho Ser1070) AntibodyTarget Information

Gene Symbol EGFR
Alternative Names
ERBB
HER1
mENA
ERBB1
PIG61
Receptor protein-tyrosine kinase ErbB-1
kinase EGFR
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Molecular Weight(MW) 175 kDa
Tissue Specificity This antibody detects endogenous level of EGFR only when phosphorylated at serine1070.

EGFR (phospho Ser1070) AntibodyDatabase Links

Entrez Gene 1956
Protein Accession NP_005219.2

EGFR (phospho Ser1070) AntibodyApplication

  • Application

    Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using EGFR (Phospho-Ser1070).

  • Application

    Western blot analysis of lysed extracts from HUVEC cells untreated or treated with EGF using EGFR (Phospho-Ser1070).

Application Notes
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:

Additional Information

Form Liquid
Storage Instructions Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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