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EGFR (phospho Tyr1172) Antibody

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产品名称: EGFR (phospho Tyr1172) Antibody
产品型号:
产品展商: immunoclone
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简单介绍

EGFR (phospho Tyr1172) Antibody迅速增长的产品线包括一抗、二抗、**测定及细胞检测试剂盒、蛋白/多肽、激动剂/拮抗剂/活化剂/抑制剂及裂解物等。EGFR (phospho Tyr1172) Antibody严格的质量控制和验证实验包括各种不同的应用：WB、细胞**荧光、**组化、流式细胞术、ELISA、CHIP、IP和peptide array。


EGFR (phospho Tyr1172) Antibody  的详细介绍

EGFR (phospho Tyr1172) AntibodyProduct Profile

Product Name EGFR (phospho Tyr1172) Antibody
Antibody Type Primary Antibodies
Product description 
					

						Receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with SRC and CTNNB1/beta-catenin.1) Noguchi T, et al. (1994) Mol Cell Biol 14 (10): 6674-6682Doherty JK, et al. (1999) Proc Natl Acad Sci U S A 96 (19): 10869-10874Kanner SB, et al. (1991) Mol Cell Biol 11 (2): 713-720Wu TT, et al. (1998) Mol Biol Cell 9 (7): 1661-1674O’Rourke DM, et al. (1997) Proc Natl Acad Sci U S A 94 (7): 3250-3255
					

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Immunogen 
EGFR (Phospho-Tyr1172) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 1172 (P-D-Y (p) -Q-Q) derived from Human EGFR.

EGFR (phospho Tyr1172) AntibodyKey Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

IHCWB

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
Species Reactivity

HumanMouseRat

Concentration 1mg/ml
Purification Affinity purified

EGFR (phospho Tyr1172) AntibodyTarget Information

Gene Symbol EGFR
Alternative Names
ERBB
HER1
mENA
ERBB1
PIG61
NBS
NBS1
P95
Receptor protein-tyrosine kinase ErbB-1
kinase EGFR
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Molecular Weight(MW) 175 kDa
Tissue Specificity This antibody detects endogenous level EGFR only when phosphorylated at tyrosine 1172.

EGFR (phospho Tyr1172) AntibodyDatabase Links

Entrez Gene 1956
Protein Accession NP_005219.2

EGFR (phospho Tyr1172) AntibodyApplication

  • Application

    Western blot analysis of lysed extracts from A431 cells untreated or treated with EGF using EGFR (Phospho-Tyr1172).

  • Application

    Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using EGFR (Phospho-Tyr1172).

Application Notes
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:

Additional Information

Form Liquid
Storage Instructions Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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