产品资料

p70 S6 Kinase (phospho Ser411) Antibody

如果您对该产品感兴趣的话,可以
产品名称: p70 S6 Kinase (phospho Ser411) Antibody
产品型号:
产品展商: immunoclone
产品文档: 无相关文档

简单介绍

p70 S6 Kinase (phospho Ser411) Antibody迅速增长的产品线包括一抗、二抗、**测定及细胞检测试剂盒、蛋白/多肽、激动剂/拮抗剂/活化剂/抑制剂及裂解物等。p70 S6 Kinase (phospho Ser411) Antibody严格的质量控制和验证实验包括各种不同的应用：WB、细胞**荧光、**组化、流式细胞术、ELISA、CHIP、IP和peptide array。


p70 S6 Kinase (phospho Ser411) Antibody  的详细介绍

p70 S6 Kinase (phospho Ser411) AntibodyProduct Profile

Product Name p70 S6 Kinase (phospho Ser411) Antibody
Antibody Type Primary Antibodies
Product description 
					

						Phosphorylates specifically ribosomal protein S6 in response to insulin or several classes of mitogens. Promotes protein synthesis by phosphorylating PDCD4 at 'Ser-67' and targeting it for degradation.1) Satoru Eguchi et al. (1999) J Biol Chem, Vol. 274: 36843-36851Papst PJ, et al. (1998) J Biol Chem. 273 (24): 15077-84. Ulrike Krause et al. (2002) Eur. J. Biochem. 269: 3751-3759 cLe, X. F, et al. (2003) Oncogene 22: 484–97
					

More 
Immunogen 
p70 S6 Kinase (Phospho-Ser411) antibody was raised against a peptide sequence around phosphorylation site of serine 411 (I-R-S (p) -P-R) derived from Human p70 S6 Kinase.

p70 S6 Kinase (phospho Ser411) AntibodyKey Feature

Clonality Polyclonal
Host Species Rabbit
Species Reactivity

Human

Concentration 1mg/ml
Purification Affinity purified

p70 S6 Kinase (phospho Ser411) AntibodyTarget Information

Gene Symbol RPS6KB1
Alternative Names
S6K
PS6K
S6K1
STK14A
p70-S6K
p70S6KA
p70-alpha
S6K-beta-1
p70(S6K)-alpha
MACS
PRKCSL
KS6B1
P70-S6K
RPS6KB1
S6K
More 
Molecular Weight(MW) 70 85 kDa
Tissue Specificity This antibody detects endogenous level of p70 S6 Kinase only when phosphorylated at serine 411.

p70 S6 Kinase (phospho Ser411) AntibodyDatabase Links

Entrez Gene 6198
Protein Accession NP_003152.1

p70 S6 Kinase (phospho Ser411) AntibodyApplication

  • Application

    Top Image: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p70 S6 Kinase (Phospho-Ser411). Bottom Image: Immunofluorescence staining of methanol-fixed MCF7 cells using p70 S6 Kinase (Phospho-Ser411).

  • Application

    Western blot analysis of lysed extracts from MCF cells untreated or treated with EGF using p70 S6 Kinase (Phospho-Ser411).

Application Notes
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200:

Additional Information

Form Liquid
Storage Instructions Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

沪公网安备 31011702004356号