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14 3 3 zeta Antibody

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产品名称: 14 3 3 zeta Antibody
产品型号:
产品展商: immunoclone
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简单介绍

14 3 3 zeta Antibody迅速增长的产品线包括一抗、二抗、**测定及细胞检测试剂盒、蛋白/多肽、激动剂/拮抗剂/活化剂/抑制剂及裂解物等。14 3 3 zeta Antibody严格的质量控制和验证实验包括各种不同的应用:WB、细胞**荧光、**组化、流式细胞术、ELISA、CHIP、IP和peptide array。


14 3 3 zeta Antibody  的详细介绍

14 3 3 zeta AntibodyProduct Profile

Product Name 14 3 3 zeta Antibody
Antibody Type Primary Antibodies
Product description
					
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.1) Gu YM, et al. (2006) FEBS Lett ; 580 (1): 305-310Powell DW, et al. (2003) Mol Cell Biol; 23 (15): 5376-5387Mackintosh C. (2004) Biochem J; 381 (Pt 2): 329-342.
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Immunogen
14-3-3 zeta (Ab-58) antibody was raised against a peptide sequence around aa.56~60 (R-S-S-W-R) derived from Human 14-3-3 zeta.

14 3 3 zeta AntibodyKey Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

IHCWB

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
Species Reactivity

HumanMouseRat

Concentration 1mg/ml
Purification Affinity purified

14 3 3 zeta AntibodyTarget Information

Gene Symbol YWHAZ
Molecular Weight(MW) 28 kDa
Tissue Specificity This antibody detects endogenous level of total 14-3-3 zeta protein.

14 3 3 zeta AntibodyDatabase Links

Entrez Gene 7534
Protein Accession NP_001129171.1

14 3 3 zeta AntibodyApplication

  • Application

    (4µg/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining. Similar results were obtained after antigen retrieval at pH 9.

Application Notes
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:

Additional Information

Form Liquid
Storage Instructions Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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