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HER2 (phospho Tyr1221 / Tyr1222) Antibody

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产品名称: HER2 (phospho Tyr1221 / Tyr1222) Antibody
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产品展商: immunoclone
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简单介绍

HER2 (phospho Tyr1221 / Tyr1222) Antibody迅速增长的产品线包括一抗、二抗、**测定及细胞检测试剂盒、蛋白/多肽、激动剂/拮抗剂/活化剂/抑制剂及裂解物等。HER2 (phospho Tyr1221 / Tyr1222) Antibody严格的质量控制和验证实验包括各种不同的应用：WB、细胞**荧光、**组化、流式细胞术、ELISA、CHIP、IP和peptide array。


HER2 (phospho Tyr1221 / Tyr1222) Antibody  的详细介绍

HER2 (phospho Tyr1221 / Tyr1222) AntibodyProduct Profile

Product Name HER2 (phospho Tyr1221 / Tyr1222) Antibody
Antibody Type Primary Antibodies
Product description 
					

						Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Not activated by EGF, TGF-alpha and amphiregulin.1) Marone R, et al. (2004) Nat Cell Biol; 6 (6): 515-22. Ren Z, et al. (2002) J Biol Chem; 277 (41): 38486-93.
					

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Immunogen 
HER2 (Phospho-Tyr1221/Tyr1222) antibody was raised against a peptide sequence around phosphorylation site of tyrosine1221/1222 (N-L-Y (p) -Y (p) -W) derived from Human HER2.

HER2 (phospho Tyr1221 / Tyr1222) AntibodyKey Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

IFWB

Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200:
Species Reactivity

HumanMouse

Concentration 1mg/ml
Purification Affinity purified

HER2 (phospho Tyr1221 / Tyr1222) AntibodyTarget Information

Gene Symbol ERBB2
Alternative Names
NEU
NGL
HER2
TKR1
CD340
HER-2
MLN19
HER-2/neu
GP3A
C-erbB-2
ErbB2
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Molecular Weight(MW) 185 kDa
Tissue Specificity This antibody detects endogenous level of HER2 only when phosphorylated at tyrosine1221/tyrosine1222.

HER2 (phospho Tyr1221 / Tyr1222) AntibodyDatabase Links

Entrez Gene 2064
Protein Accession NP_001005862.1

HER2 (phospho Tyr1221 / Tyr1222) AntibodyApplication

  • Application

    Immunofluorescence staining of methanol-fixed MCF cells using HER2 (Phospho-Tyr1221/Tyr1222).

  • Application

    Western blot analysis of lysed extracts from MDA cells untreated or treated with EGF using HER2 (Phospho-Tyr1221/Tyr1222).

Application Notes
Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200:

Additional Information

Form Liquid
Storage Instructions Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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