Smad3 encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.1) Cohen-Solal KA, et al. (2011) Pigment Cell Melanoma Res 24, 512-24 More
Smad3 (phospho Ser204) antibody was raised against a peptide sequence around phosphorylation site of serine204 (A-G-S (p)-P-N) derived from Human Smad3 .
WB
HumanMouseRat
Western blot analysis of extracts from NIH-3T3 cells treated with Serum using Phospho-Smad3 (Ser204) Antibody. The lane on the right is treated with the antigen-specific peptide.
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