This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Alternatively spliced transcript variants encoding the same protein have been identified.1) Zhu X.-X., J. Biol. Chem. 264:14556-14560(1989). More
STMN1 (phospho Ser62) antibody was raised against a peptide sequence around phosphorylation site of Serine 62 (R-R-K (p)-S-H) derived from Human STMN1.
IHCWB
HumanMouseRat
Western blot analysis of extracts from COS cells treated with nocodazole using STMN1 (Phospho-Ser62) Antibody. The lane on the right is treated with the antigen-specific peptide.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using STMN1 (Phospho-Ser62) antibody (left) or the same antibody preincubated with blocking peptide (right).
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