Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.1) Murchie R, et al. (2014)Proc Natl Acad Sci U S A 111, 693-8. Kawahara T, et al. (2013)PLoS One 8, e79654 . Wang Y, Lazo JS (2012)Oncogene 31, 818-27. More
Ezrin (phospho Tyr146) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 146 (S-G-Y (p)-L-S) derived from Human Ezrin.
WB
HumanMouseRat
Western blot analysis of extracts from 293 cells treated with UV using Phospho-Ezrin (Tyr146) Antibody. The lane on the right is treated with the antigen-specific peptide.
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