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Mouse Irak1 Antibody

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产品名称: Mouse Irak1 Antibody
产品型号:
产品展商: immunoclone
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简单介绍

Mouse Irak1 Antibody迅速增长的产品线包括一抗、二抗、**测定及细胞检测试剂盒、蛋白/多肽、激动剂/拮抗剂/活化剂/抑制剂及裂解物等。Mouse Irak1 Antibody严格的质量控制和验证实验包括各种不同的应用:WB、细胞**荧光、**组化、流式细胞术、ELISA、CHIP、IP和peptide array。


Mouse Irak1 Antibody  的详细介绍

Mouse Irak1 AntibodyProduct Profile

Product Name Mouse Irak1 Antibody
Antibody Type Primary Antibodies
Product description
					
Irak1 binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. The kinase activity of this enzyme may not be required for IL-1 signaling. Once phosphorylated, IRAK1 recruits the adapter protein PELI1.1) Vaughan, T., et al. Mol. Immunol. 47(15):2515-2518(2010)
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Immunogen
This Mouse Irak1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 405-433 amino acids from the Central region of mouse Irak1.

Mouse Irak1 AntibodyKey Feature

Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications

FACSWB

For WB starting dilution is: 1:1000 For FACS starting dilution is: 1:10~50:
Species Reactivity

Mouse

Concentration 1mg/ml
Purification Affinity purified

Mouse Irak1 AntibodyTarget Information

Gene Symbol Irak1
Alternative Names
Interleukin-1 receptor-associated kinase 1
IRAK
IRAK-1
Pelle-like protein kinase
mPLK
Irak1
Il1rak
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Molecular Weight(MW) 77 kDa

Mouse Irak1 AntibodyDatabase Links

Entrez Gene 16179
Protein Accession Q62406

Mouse Irak1 AntibodyApplication

  • Application

    Western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).

  • Application

    Flow cytometric analysis of Neuro-2a cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.

Application Notes
For WB starting dilution is: 1:1000 For FACS starting dilution is: 1:10~50:

Additional Information

Form Liquid
Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.

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