Transcription factor that binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA.1) Heim M H, (1999) J Recept Signal Transduct Res. 19: 75-120. Takeda K, et al. (1997) Proc Natl Acad Sci USA. 94: 3801-3804. Catlett-Falcone R, et al. (1999) Immunity. 10: 105-115. Garcia R, et al. (1998) J Biomed Sci. 5: 79-85. Bromberg J F, et al. (1999) Cell. 98: 295-303. More
STAT3 (Phospho-Ser727) antibody was raised against a peptide sequence around phosphorylation site of serine 727 (P-M-S (p) -P-R) derived from Human STAT3.
IFIHCWB
HumanMouseRat
Western blot analysis of lysed extracts from HeLa and HepG2 cells untreated or treated with PMA using STAT3 (Phospho-Ser727).
Top Image: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using STAT3 (Phospho-Ser727). Bottom Image: Immunofluorescence staining of methanol-fixed HeLa cells using STAT3 (Phospho-Ser727).
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