PROTEINS

MMPs

S100s

SOD

IDPs

COPPER PROTEINS

OTHER PROTEINS

CUSTOM SERVICES

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READY-TO-USE NMR STANDARDS

Giotto Biotech has a strategic agreement with CortecNet that allows us to provide the NMR community with a number of NMR protein reference standards at very competitive prices. Solution and solid-state NMR standards are available, provided “ready-to-use” in tubes or pre-packed in rotors.

SOLUTION NMR	SOLID_STATE NMR

METABOLOMICS SERVICES

FOR THE BIOMEDICAL, PHARMACEUTICAL, AGRO-FOOD AND PROBIOTIC SECTORS

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NMR-BASED METABOLOMICS

Pairing the power of nuclear magnetic resonance (NMR) 
with the science of metabolomics to provide you with 
state-of-the-art services for your key applications 

Giotto Biotech, in collaboration with the FiorGen Foundation and the Magnetic Resonance Center (CERM) at the University of Florence, is in a unique position to provide you with metabolomics services thanks to access to top-of-the-line instrumentation (including a fully robotized 600 MHz NMR machine for high volumes, a 600 MHz HR-MAS, and an 850 MHz solid-state machine for metabolomics on tissue extracts). 

Some examples of the fields of application: 

• Biomedical: metabolomic profiling of biological fluIDS (breath condensate, expectorate, sweat, urine, blood, serum), disease fingerprinting 
• Pharmaceutical: prediction of drug toxicity, analysis of mechanism of action and side effects 
• Agro-food: analyses of food products (fruits, vegetables, dairy products, olive oil, meat and fish, etc.) 
• Probiotic: metabolomics of probiotic products for their characterization 

Advantages of metabolomics by NMR

As compared to metabolomics by mass spectrometry, metabolomics by NMR:

• is more accurate (though metabolomics by mass spectrometry is more sensitive)
• does not require the destruction of samples
• involves easier sample preparation
• is faster

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NMR ACCESS

Giotto Biotech provides NMR for structure determination, assignment, and screening.

A complete battery of NMR instrumentation (solution and solid state), ranging from 600 to 950 MHz, including an 850 MHz for solid-state, is available to meet the most disparate experimental conditions thanks to a close collaboration with the Interuniversity Consortium for Magnetic Resonance (CIRMMP), which also guarantees the quality of the services.

A preliminary HSQC is requested, or can be measured by us, to decide the quality of the spectra and the time required for the service.

Advanced LIMS are available to meet the needs of industry.